Radiation Effects on Human Lymphocytes Stimulated by Phytohemagglutinin
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چکیده
منابع مشابه
Adenosine metabolism in phytohemagglutinin-stimulated human lymphocytes.
The association of a human genetic deficiency of adenosine deaminase activity with combined immunodeficiency prompted a study of the effects of adenosine and of inhibition of adenosine deaminase activity on human lymphocyte transformation and a detailed study of adenosine metabolism throughout phytohemagglutinin-induced blastogenesis. The adenosine deaminase inhibitor, coformycin, at a concentr...
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Poliovirus replication has been studied in human lymphocytes during the course of blastogenesis under phytohemagglutinin (PHA) stimulation. Enhancement of virus replication in PHA-stimulated leukocyte cultures was due to an increase in number of virus-producing cells. Virus yield was approximately 10 plaque-forming units (PFU) per producing cell, both in stimulated and in nonstimulated cultures...
متن کاملA method for counting phytohemagglutinin-stimulated lymphocytes.
I T HAS BEEN SHOWN that peripheral i)lood lynlphocvtes undergo trainsformation and mitosis in vitro when cultured in the presence of plwtohemagglutinin ( PHA).’4 Little information has been reported on the numl)er of lymphocytes which survive and transform during the culturing interval. It has been very difficult to enumerate lymphocytes in cultures containing PFIA I)ecause the agglutinated ery...
متن کاملInhibition of mitosis by chloramphenicol in phytohemagglutinin stimulated lymphocytes.
I TARIOUS CLINICAL AND EXPERIMENTAL STUDIES have shown V that chioramphenicol ( CAP) affects cell division. #{176} The characteristic aplastic marrow that is seen when toxicity is fully expressed suggests a toxic effect leading to depletion of dividing cells. The effect of CAP on incorporation of 32 into phytohemagglutinin ( PHA) stimulated lymphocytes was reported by McIntyre and Ebaugh,’ who ...
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By JEROME I. BRODY AND HENRY D. SOLTYS T HE PUBPOSE of this study was to delineate the durability and persistence of immunologic recall in the normal peripheral blood lymphocyte using methods which might reflect the importance of the manner by which imniunologic information is acquired. This was done in the present investigation with the technic of bacterial adherence,”2 in which circumferentia...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 1970
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.100.375